Abstract
Objective
To describe the perioperative changes in blood pancreatic lipase activity and explore the contributing clinical factors associated with these changes.
Design
Prospective observational study.
Setting
University teaching hospital.
Animals
One hundred and four dogs underwent various surgical procedures under general anesthesia.
Interventions
None.
Measurements and Main Results
Blood pancreatic lipase activities, which were measured using FUJI DRI-CHEM v-Lip-P (FDC-v-Lip), significantly increased postoperatively compared to preoperative measurements (premedian 58.5 U/L [range, 23–157] vs. postmedian 80 U/L [range, 22–1000], P < 0.0001). The patient with a postoperative increase in FDC-v-Lip over the normal range (35 dogs [33.6%]) had significantly higher preoperative FDC-v-Lip values.
Conclusions
In this study, dogs had significantly increased pancreas-specific lipase activities after surgical procedures under general anesthesia. Direct contributors to the increase and its relevance to clinical and histological pancreatitis should be determined in the future.
Journal of Veterinary Emergency and Critical Care, EarlyView.Wiley: Journal of Veterinary Emergency and Critical Care: Table of Contents